Endometriosis, Angiogenesis and Tissue Factor
نویسندگان
چکیده
منابع مشابه
Endometriosis, Angiogenesis and Tissue Factor
Tissue factor (TF), is a cellular receptor that binds the factor VII/VIIa to initiate the blood coagulation cascade. In addition to its role as the initiator of the hemostatic cascade, TF is known to be involved in angiogenesis via intracellular signaling that utilizes the protease activated receptor-2 (PAR-2). We now review the physiologic expression of TF in the endometrium and its altered ex...
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Tissue factor (TF) contributes to a variety of biological processes by generating coagulation proteases and by the activation of protease activated receptors (PARs). Studies, using low TF mice, have provided us with novel insights into the role of TF in tissue-specific haemostasis. Low TF mice exhibit defects in the uterus, placenta, heart and lung, which are all tissues that normally express h...
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ژورنال
عنوان ژورنال: Scientifica
سال: 2012
ISSN: 2090-908X
DOI: 10.6064/2012/306830